CPL: An approach to identify protein complexes



Detecting protein Complexes by Propagating Labels through PPI network


CPL is a graph clustering software, which is designed to detect protein complexes in protein-protein network (PPI). It detects the complexes by propagating labels, which is to simulate the interacting activities of proteins.

The paper in the following which describes the CPL method has been submitted to Bioinformatics.

[1] Qiguo Dai, Maozu Guo, Xiaoyan Liu,Zhixia Teng and Chunyu Wang. CPL: Detecting protein Complexes by Propagating Labels through protein-protein network. Journal of Computer Science and Technology, 2014, 29(6): 1083-1093.



The software of CPL and its Manual can be downloaded.

Some PPI networks of yeast we used in experiments are avaliable.




This work was supported by:

  1.Natural Science Foundation of China;

  2.Specialized Research Fund for the Doctoral Program of Higher Education of China;

  3.Fundamental Research Funds for the Central Universities.



Email: qiguo_dai@hit.edu.cn or maozuguo@hit.edu.cn

By Nature Computation lab (NCLab) , Harbin Institute of Technology, China, 150001